Tyrosine phosphorylation in Toll-like receptor signaling
S Chattopadhyay, GC Sen - Cytokine & growth factor reviews, 2014 - Elsevier
There is a wealth of knowledge about how different Ser/Thr protein kinases participate in
Toll-like receptor (TLR) signaling. In many cases, we know the identities of the Ser/Thr
residues of various components of the TLR-signaling pathways that are phosphorylated, the
functional consequences of the phosphorylation and the responsible protein kinases. In
contrast, the analysis of Tyr-phosphorylation of TLRs and their signaling proteins is currently
incomplete, because several existing analyses are not systematic or they do not rely on …
Toll-like receptor (TLR) signaling. In many cases, we know the identities of the Ser/Thr
residues of various components of the TLR-signaling pathways that are phosphorylated, the
functional consequences of the phosphorylation and the responsible protein kinases. In
contrast, the analysis of Tyr-phosphorylation of TLRs and their signaling proteins is currently
incomplete, because several existing analyses are not systematic or they do not rely on …