[HTML][HTML] Early chronic low-level lead exposure produces glomerular hypertrophy in young C57BL/6J mice
Early chronic lead exposure continues to pose serious health risks for children, particularly
those living in lower socioeconomic environments. This study examined effects on
developing glomeruli in young C57BL/6J mice exposed to low (30 ppm), higher (330 ppm)
or no lead via dams' drinking water from birth to sacrifice on post-natal day 28. Low-level
lead exposed mice [BLL mean (SD); 3.19 (0.70) μg/dL] had an increase in glomerular
volume but no change in podocyte number compared to control mice [0.03 (0.01) μg/dL] …
those living in lower socioeconomic environments. This study examined effects on
developing glomeruli in young C57BL/6J mice exposed to low (30 ppm), higher (330 ppm)
or no lead via dams' drinking water from birth to sacrifice on post-natal day 28. Low-level
lead exposed mice [BLL mean (SD); 3.19 (0.70) μg/dL] had an increase in glomerular
volume but no change in podocyte number compared to control mice [0.03 (0.01) μg/dL] …
