The release of microRNA‐122 during liver preservation is associated with early allograft dysfunction and graft survival after transplantation
JW Selten, CJ Verhoeven, V Heedfeld… - Liver …, 2017 - journals.lww.com
Early allograft dysfunction (EAD) after liver transplantation (LT) is associated with inferior
graft survival. EAD is more prevalent in grafts from donation after circulatory death (DCD).
However, accurate prediction of liver function remains difficult because of the lack of specific
biomarkers. Recent experimental and clinical studies highlight the potential of hepatocyte‐
derived microRNAs (miRNAs) as sensitive, stable, and specific biomarkers of liver injury.
The aim of this study was to determine whether miRNAs in graft preservation fluid are …
graft survival. EAD is more prevalent in grafts from donation after circulatory death (DCD).
However, accurate prediction of liver function remains difficult because of the lack of specific
biomarkers. Recent experimental and clinical studies highlight the potential of hepatocyte‐
derived microRNAs (miRNAs) as sensitive, stable, and specific biomarkers of liver injury.
The aim of this study was to determine whether miRNAs in graft preservation fluid are …