Safety and tolerability of prescription omega-3 fatty acids: A systematic review and meta-analysis of randomized controlled trials

CH Chang, PT Tseng, NY Chen, PC Lin, PY Lin… - … and Essential Fatty …, 2018 - Elsevier
Background Omega-3 fatty acids [eicosapentaenoic acid (EPA) and docosahexaenoic acid
(DHA)] are widely recommended for health promotion. Over the last decade, prescription
omega-3 fatty acid products (RxOME3FAs) have been approved for medical indications.
Nonetheless, there is no comprehensive analysis of safety and tolerability of RxOME3FAs so
far. Methods A systematic review of randomized controlled trials (RCTs) was carried out
based on searches in six electronic databases. The studies involving marketed RxOME3FA …