Lipomatous pseudohypertrophy of the pancreas: a clinicopathologically distinct entity

D Altinel, O Basturk, JM Sarmiento, D Martin… - Pancreas, 2010 - journals.lww.com
Pancreas, 2010journals.lww.com
Objectives: Owing to the challenges in obtaining pancreatic biopsies, pancreatic resection
for presumed malignancy is often performed without histological confirmation. As a result,
benign lesions are sometimes surgically removed. One such condition, which is poorly
defined in the literature, is referred to as lipomatous pseudohypertrophy (LPH) of the
pancreas. Methods: Five cases of LPH were analyzed. Results: Four patients underwent
surgical resection, 3 of which were diagnosed preoperatively by radiology as having ductal …
Abstract
Objectives:
Owing to the challenges in obtaining pancreatic biopsies, pancreatic resection for presumed malignancy is often performed without histological confirmation. As a result, benign lesions are sometimes surgically removed. One such condition, which is poorly defined in the literature, is referred to as lipomatous pseudohypertrophy (LPH) of the pancreas.
Methods:
Five cases of LPH were analyzed.
Results:
Four patients underwent surgical resection, 3 of which were diagnosed preoperatively by radiology as having ductal adenocarcinoma. The fourth case was correctly interpreted by magnetic resonance imaging as LPH, but the patient underwent resection because of the intractable pain due to pancreatitis. The fifth patient has been placed on watchful waiting.
Lippincott Williams & Wilkins