[HTML][HTML] Severe pyoderma gangrenosum caused by myelodysplastic syndrome successfully treated with decitabine administered by a noncytotoxic regimen

MFM Saleh, Y Saunthararajah - Clinical Case Reports, 2017 - ncbi.nlm.nih.gov
MFM Saleh, Y Saunthararajah
Clinical Case Reports, 2017ncbi.nlm.nih.gov
Pyoderma gangrenosum (PG) is a morbid necrotizing neutrophilic dermatoses for which
current treatments are inadequate. Here, we describe the use of a novel noncytotoxic
regimen of the deoxycytidine analog decitabine to treat underlying myeloid malignancy
causing PG, to thereby produce safe and effective resolution of extensive PG.
Pyoderma gangrenosum (PG) is a morbid necrotizing neutrophilic dermatoses for which current treatments are inadequate. Here, we describe the use of a novel noncytotoxic regimen of the deoxycytidine analog decitabine to treat underlying myeloid malignancy causing PG, to thereby produce safe and effective resolution of extensive PG.
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