Maternal exposure to herpes simplex virus and risk of psychosis among adult offspring
SL Buka, TD Cannon, EF Torrey, RH Yolken… - Biological …, 2008 - Elsevier
BACKGROUND: Viral exposure during gestation is thought to be a risk factor for
schizophrenia. Previous studies have indicated that prenatal exposure to herpes simplex
virus type 2 (HSV-2) may be a risk for the subsequent development of schizophrenia in
some populations. In this investigation, we tested a large and diverse population to assess
the risk of psychoses among offspring of mothers with serological evidence of HSV-2
infection. METHODS: We conducted a nested case-control study of 200 adults with …
schizophrenia. Previous studies have indicated that prenatal exposure to herpes simplex
virus type 2 (HSV-2) may be a risk for the subsequent development of schizophrenia in
some populations. In this investigation, we tested a large and diverse population to assess
the risk of psychoses among offspring of mothers with serological evidence of HSV-2
infection. METHODS: We conducted a nested case-control study of 200 adults with …