[HTML][HTML] A solute carrier family 22 member 3 variant rs3088442 G→ A associated with coronary heart disease inhibits lipopolysaccharide-induced inflammatory …

L Li, M He, L Zhou, X Miao, F Wu, S Huang… - Journal of Biological …, 2015 - ASBMB
Recent genome-wide association studies have identified single-nucleotide polymorphism
(SNPs) within the SLC22A3 (solute carrier family 22 member 3) gene associated with
coronary heart disease (CHD) in the Caucasian population. We performed molecular
analysis to investigate the potential role of SLC22A3 variants in CHD. Our study showed that
the common polymorphism rs3088442 G→ A, which is localized in the 3′ UTR of the
SLC22A3 gene, was associated with a decreased risk of CHD in the Chinese population by …