[PDF][PDF] Fat uses a TOLL-road to connect inflammation and diabetes
JK Kim - Cell metabolism, 2006 - cell.com
JK Kim
Cell metabolism, 2006•cell.comThe link between inflammation and diabetes is well established, but the nature of the link is
unresolved. Obesity, inflammation, and insulin resistance are major characteristics of
diabetes. A study by Flier and colleagues (Shi et al., 2006) identifies Toll-like receptor 4
signaling activated by fatty acids as part of that link. This receptor mediates inflammatory
events and insulin resistance in peripheral organs.
unresolved. Obesity, inflammation, and insulin resistance are major characteristics of
diabetes. A study by Flier and colleagues (Shi et al., 2006) identifies Toll-like receptor 4
signaling activated by fatty acids as part of that link. This receptor mediates inflammatory
events and insulin resistance in peripheral organs.
The link between inflammation and diabetes is well established, but the nature of the link is unresolved. Obesity, inflammation, and insulin resistance are major characteristics of diabetes. A study by Flier and colleagues (Shi et al., 2006) identifies Toll-like receptor 4 signaling activated by fatty acids as part of that link. This receptor mediates inflammatory events and insulin resistance in peripheral organs.
cell.com