Energy requirement for sodium reabsorption in the in vivo rabbit kidney

G Torelli, E Milla, A Faelli… - American Journal of …, 1966 - journals.physiology.org
G Torelli, E Milla, A Faelli, S Costantini
American Journal of Physiology-Legacy Content, 1966journals.physiology.org
METHODS The experiments were performed on male rabbits, weighing from 2. I to 2.5 kg
and lightly anesthetized with a mixture of pentobarbital and urethan (0.5 ml/kg of a solution
of 20% urethan and 3% pentobarbital in physiological solution). The amount of reabsorbed
Na+ was calculated as the difference between the filtered and excreted Pia f. The value of
filtered sodium was determined by multiplying the Na+ concentration in plasma and the
inulin clearance. The oxygen consumption and the lactic acid production were obtained by …
METHODS
The experiments were performed on male rabbits, weighing from 2. I to 2.5 kg and lightly anesthetized with a mixture of pentobarbital and urethan (0.5 ml/kg of a solution of 20% urethan and 3% pentobarbital in physiological solution). The amount of reabsorbed Na+ was calculated as the difference between the filtered and excreted Pia f. The value of filtered sodium was determined by multiplying the Na+ concentration in plasma and the inulin clearance. The oxygen consumption and the lactic acid production were obtained by multiplying, respectively, the arteriovenous 02 difference and the venous-arterial lactic acid difference and the renal blood flow. The general schema of the apparatus is given in Fig. I. The extracorporeal circulation
American Physiological Society