On the role of differential adhesion in gangliogenesis in the enteric nervous system
EJ Hackett-Jones, KA Landman, DF Newgreen… - Journal of theoretical …, 2011 - Elsevier
A defining characteristic of the normal development of the enteric nervous system (ENS) is
the existence of mesoscale patterned entities called ganglia. Ganglia are clusters of neurons
with associated enteric neural crest (ENC) cells, which form in the simultaneously growing
gut wall. At first the precursor ENC cells proliferate and gradually differentiate to produce the
enteric neurons; these neurons form clusters with ENC scattered around and later lying on
the periphery of neuronal clusters. By immunolabelling neural cell–cell adhesion molecules …
the existence of mesoscale patterned entities called ganglia. Ganglia are clusters of neurons
with associated enteric neural crest (ENC) cells, which form in the simultaneously growing
gut wall. At first the precursor ENC cells proliferate and gradually differentiate to produce the
enteric neurons; these neurons form clusters with ENC scattered around and later lying on
the periphery of neuronal clusters. By immunolabelling neural cell–cell adhesion molecules …