Sex differences in experimental autoimmune encephalomyelitis in multiple murine strains
TL Papenfuss, CJ Rogers, I Gienapp, M Yurrita… - Journal of …, 2004 - Elsevier
Multiple sclerosis (MS) is more prevalent in women than men. We evaluated seven different
mouse strains commonly used in the study of autoimmune diseases, for sex differences in
the disease course of experimental autoimmune encephalomyelitis (EAE). Greater severity
of EAE was observed in the female SJL immunized with two different peptides of myelin
proteolipid protein (PLP) and myelin oligodendrocyte glycoprotein (MOG) as well as in the
female ASW relative to males. Female NZW mice showed a greater incidence of EAE than …
mouse strains commonly used in the study of autoimmune diseases, for sex differences in
the disease course of experimental autoimmune encephalomyelitis (EAE). Greater severity
of EAE was observed in the female SJL immunized with two different peptides of myelin
proteolipid protein (PLP) and myelin oligodendrocyte glycoprotein (MOG) as well as in the
female ASW relative to males. Female NZW mice showed a greater incidence of EAE than …