[HTML][HTML] Role of acyl-CoA binding protein in acyl-CoA metabolism and acyl-CoA–mediated cell signaling
J Knudsen, TBF Neergaard, B Gaigg, MV Jensen… - The Journal of …, 2000 - Elsevier
Long-chain acyl-CoA esters (LCA) act both as substrates and intermediates in metabolism
and as regulators of various intracellular functions. Acyl-CoA binding protein (ACBP) binds
LCA with high affinity and is believed to play an important role in intracellular acyl-CoA
transport and pool formation and therefore also for the function of LCA as metabolites and
regulators of cellular functions. The free concentration of cytosolic LCA is efficiently buffered
to low nanomole concentration by ACBP and fatty acid binding protein (FABP). An additional …
and as regulators of various intracellular functions. Acyl-CoA binding protein (ACBP) binds
LCA with high affinity and is believed to play an important role in intracellular acyl-CoA
transport and pool formation and therefore also for the function of LCA as metabolites and
regulators of cellular functions. The free concentration of cytosolic LCA is efficiently buffered
to low nanomole concentration by ACBP and fatty acid binding protein (FABP). An additional …