[HTML][HTML] Expression of Sox8, Sox9 and Sox10 in the developing valves and autonomic nerves of the embryonic heart
JA Montero, B Giron, H Arrechedera, YC Cheng… - Mechanisms of …, 2002 - Elsevier
JA Montero, B Giron, H Arrechedera, YC Cheng, P Scotting, J Chimal-Monroy…
Mechanisms of development, 2002•ElsevierWe describe the expression pattern of Sox8, Sox9 and Sox10 during the development of the
chick embryo heart. These Sox genes constitute the group E of the large Sox family of
transcription factors. We show that the expression of Sox8, Sox9 and Sox10 in the
developing heart correlates with heart septation and with the differentiation of the connective
tissue of the valve leaflets. Sox10 appears also as a specific marker of developing heart
nerves. These findings fit with the occurrence of morphological and functional anomalies of …
chick embryo heart. These Sox genes constitute the group E of the large Sox family of
transcription factors. We show that the expression of Sox8, Sox9 and Sox10 in the
developing heart correlates with heart septation and with the differentiation of the connective
tissue of the valve leaflets. Sox10 appears also as a specific marker of developing heart
nerves. These findings fit with the occurrence of morphological and functional anomalies of …
We describe the expression pattern of Sox8, Sox9 and Sox10 during the development of the chick embryo heart. These Sox genes constitute the group E of the large Sox family of transcription factors. We show that the expression of Sox8, Sox9 and Sox10 in the developing heart correlates with heart septation and with the differentiation of the connective tissue of the valve leaflets. Sox10 appears also as a specific marker of developing heart nerves. These findings fit with the occurrence of morphological and functional anomalies of the heart reported in humans deficient for Sox9 and Sox10.
Elsevier