Leukocyte count as a predictor of cardiovascular events and mortality in postmenopausal women: the Women's Health Initiative Observational Study

KL Margolis, JAE Manson, P Greenland… - Archives of internal …, 2005 - jamanetwork.com
Background Increasing evidence supports a role for inflammation in the atherosclerotic
process. The role of the leukocyte count as an independent predictor of risk of a first
cardiovascular disease (CVD) event remains uncertain. Our objective was to describe the
relation between the baseline white blood cell (WBC) count and future CVD events and
mortality in postmenopausal women. Methods In this prospective cohort study set in 40 US
clinical centers, the study population comprised 72 242 postmenopausal women aged 50 to …