Age-related inflammatory cytokines and disease
H Brüünsgaard, BK Pedersen - … and Allergy Clinics, 2003 - immunology.theclinics.com
Studies have demonstrated that circulating levels of plasma cytokines are influenced greatly
by age and that chronic elevated levels of certain cytokines are associated with chronic
diseases. This article discusses the origin of ageassociated elevations in circulating levels of
cytokines, focusing on the multifunctional tumor necrosis factor a (TNF-a) and interleukin 6
(IL-6) and their possible biologic effects in age-associated diseases.
by age and that chronic elevated levels of certain cytokines are associated with chronic
diseases. This article discusses the origin of ageassociated elevations in circulating levels of
cytokines, focusing on the multifunctional tumor necrosis factor a (TNF-a) and interleukin 6
(IL-6) and their possible biologic effects in age-associated diseases.