Action of progesterone on preoptic thermosensitive neurones

T Nakayama, M Suzuki, N Ishizuka - Nature, 1975 - nature.com
T Nakayama, M Suzuki, N Ishizuka
Nature, 1975nature.com
FEMALE body temperature rises by about 0.5° C at or near ovulation and remains elevated
during the luteal phase of the menstrual cycle. Sustained elevation of basal body
temperature is observed also during early pregnancy. These effects have been attributed to
progesterone, but little is known about the mechanisms involved1. We have now found that
the hormone affects the activity of the thermosensitive neurones in the preoptic area of the
brain.
Abstract
FEMALE body temperature rises by about 0.5 °C at or near ovulation and remains elevated during the luteal phase of the menstrual cycle. Sustained elevation of basal body temperature is observed also during early pregnancy. These effects have been attributed to progesterone, but little is known about the mechanisms involved1. We have now found that the hormone affects the activity of the thermosensitive neurones in the preoptic area of the brain.
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