Lymphocyte DNA damage and oxidative stress in patients with iron deficiency anemia

M Aslan, M Horoz, A Kocyigit, S Ozgonül… - Mutation research …, 2006 - Elsevier
Oxidant stress has been shown to play an important role in the pathogenesis of iron
deficiency anemia. The aim of this study was to investigate the association between
lymphocyte DNA damage, total antioxidant capacity and the degree of anemia in patients
with iron deficiency anemia. Twenty-two female with iron deficiency anemia and 22 healthy
females were enrolled in the study. Peripheral DNA damage was assessed using alkaline
comet assay and plasma total antioxidant capacity was determined using an automated …