Acanthosis nigricans.

DL Rogers - Seminars in dermatology, 1991 - europepmc.org
DL Rogers
Seminars in dermatology, 1991europepmc.org
Acanthosis nigricans (AN) is a dermopathy with a distinctive appearance that facilitates its
diagnosis. Although an external condition, it is associated with a wide variety of less obvious
internal conditions, either benign or malignant. Insulin resistance figures prominently in its
benign associations and plays a primary role in its development. The development of AN in
malignant conditions remains to be explained. AN rarely requires treatment, although the
underlying condition usually does.
Acanthosis nigricans (AN) is a dermopathy with a distinctive appearance that facilitates its diagnosis. Although an external condition, it is associated with a wide variety of less obvious internal conditions, either benign or malignant. Insulin resistance figures prominently in its benign associations and plays a primary role in its development. The development of AN in malignant conditions remains to be explained. AN rarely requires treatment, although the underlying condition usually does.
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