Epigenetic mechanisms in lupus
DR Patel, BC Richardson - Current opinion in rheumatology, 2010 - journals.lww.com
DR Patel, BC Richardson
Current opinion in rheumatology, 2010•journals.lww.comA comprehensive understanding of the epigenetic mechanisms contributing to SLE will likely
enable development of new therapeutic agents and strategies that target the dysregulated
genes or correct the aberrant epigenetic modifications. Although specific agents have not yet
been tested in SLE, the studies reviewed hold promise that these approaches will be useful
in the treatment of human lupus.
enable development of new therapeutic agents and strategies that target the dysregulated
genes or correct the aberrant epigenetic modifications. Although specific agents have not yet
been tested in SLE, the studies reviewed hold promise that these approaches will be useful
in the treatment of human lupus.
Summary
A comprehensive understanding of the epigenetic mechanisms contributing to SLE will likely enable development of new therapeutic agents and strategies that target the dysregulated genes or correct the aberrant epigenetic modifications. Although specific agents have not yet been tested in SLE, the studies reviewed hold promise that these approaches will be useful in the treatment of human lupus.
Lippincott Williams & Wilkins