Current treatment of medulloblastoma: recent advances and future challenges

BR Rood, TJ MacDonald, RJ Packer - Seminars in oncology, 2004 - Elsevier
Medulloblastoma (MB) is the most common malignant brain tumor of childhood, yet it makes
up only 1% of adult brain tumors. MB is uniquely sensitive to chemotherapy and radiation,
but successful surgical resection continues to be an important component of therapeutic
success. Progress in the treatment of MB has occurred in multiple areas from improved
neurosurgical techniques, refined dosing and delivery of radiation, and optimized
chemotherapy. Tumors are currently risk-stratified as average risk or high risk depending on …