Therapeutic effects and prognostic factors in tonsillectomy patients with IgA nephropathy
T Goto, N Bandoh, T Yoshizaki, M Takahara… - Nihon Jibiinkoka …, 2007 - europepmc.org
T Goto, N Bandoh, T Yoshizaki, M Takahara, S Nonaka, Y Harabuchi
Nihon Jibiinkoka Gakkai Kaiho, 2007•europepmc.orgResults Overall remission was 39.0%. The disappearance of hematuria increased for long-
term follow-up groups, but proteinuria was unchanged. Serum BAFF levels among the two
groups did not differ significantly. Among IgAN patients, higher BAFF levels were associated
with higher serum IgA/C3 levels. The correlation was weak (p= 0.026, r= 0.407). Using 3.2
ng/ml as a cut off point, we compared cumulative improvement in those with high
pretreatment BAFF levels to those with low pretreatment levels. Those with high …
term follow-up groups, but proteinuria was unchanged. Serum BAFF levels among the two
groups did not differ significantly. Among IgAN patients, higher BAFF levels were associated
with higher serum IgA/C3 levels. The correlation was weak (p= 0.026, r= 0.407). Using 3.2
ng/ml as a cut off point, we compared cumulative improvement in those with high
pretreatment BAFF levels to those with low pretreatment levels. Those with high …
Results
Overall remission was 39.0%. The disappearance of hematuria increased for long-term follow-up groups, but proteinuria was unchanged. Serum BAFF levels among the two groups did not differ significantly. Among IgAN patients, higher BAFF levels were associated with higher serum IgA/C3 levels. The correlation was weak (p= 0.026, r= 0.407). Using 3.2 ng/ml as a cut off point, we compared cumulative improvement in those with high pretreatment BAFF levels to those with low pretreatment levels. Those with high pretreatment BAFF levels had inferior cumulative improvement in hematuria.
Conclusion
Tonsillectomy was effective in improving hematuria. BAFF appears to be a key factor in tonsillectomy among [gAN patients.
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