The effect of intracerebroventricular infusions of leptin on the immunoreactivity of neuropeptide Y and gonadotrophin releasing hormone neurons in the hypothalamus …

J Polkowska, A Wójcik-Gładysz… - Journal of Chemical …, 2006 - Elsevier
In the study we evaluated the effects of infusion of exogenous leptin to the third ventricle of
the brain on the expression of immunoreactive (ir) neuropeptide Y (NPY) neurons in the
hypothalamus and ir gonadotrophin releasing hormone (GnRH) nerve terminals in the
median eminence of prepubertal lambs in the conditions of short fasting. Merino female
sheep (n= 16) were randomly divided into four groups, two fed with standard feeds and two
fasted for 72h. One standard and one fasted groups were infused with Ringer saline …