Cytokines and chemokines in uveitis–Is there a correlation with clinical phenotype?
KGJ Ooi, G Galatowicz, VL Calder… - Clinical medicine & …, 2006 - Marshfield Clinic
Uveitis is a general term for intraocular inflammation and includes a large number of clinical
phenotypes. As a group of disorders, it is responsible for 10% of all registered blind patients
under the age of 65 years. Immune-mediated uveitis may be associated with a systemic
disease or may be localized to the eye. The pro-inflammatory cytokines interleukin (IL)-1β, IL-
2, IL-6, interferon-γ and tumor necrosis factor-α have all been detected within the ocular
fluids or tissues in the inflamed eye together with others, such as IL-4, IL-5, IL-10 and …
phenotypes. As a group of disorders, it is responsible for 10% of all registered blind patients
under the age of 65 years. Immune-mediated uveitis may be associated with a systemic
disease or may be localized to the eye. The pro-inflammatory cytokines interleukin (IL)-1β, IL-
2, IL-6, interferon-γ and tumor necrosis factor-α have all been detected within the ocular
fluids or tissues in the inflamed eye together with others, such as IL-4, IL-5, IL-10 and …