A host of abnormalities of renal structure and function accompanies advancing age. An
appreciation of methodologic considerations, including population selection, that might
confound the assessment of the effects of aging on renal function has prompted a recent
reappraisal. Earlier studies assessed the effects of aging by utilizing cross-sectional studies
and institutionalized elderly subjects, with their attendant drawbacks. Recent longitudinal
studies have utilized appropriate patient cohorts, selected for lock of renal disease, including …