Ezrin controls the macromolecular complexes formed between an adapter protein Na+/H+ exchanger regulatory factor and the cystic fibrosis transmembrane …
J Li, Z Dai, D Jana, DJE Callaway, Z Bu - Journal of Biological Chemistry, 2005 - ASBMB
Na+/H+ exchanger regulatory factor (NHERF) is an adapter protein that is responsible for
organizing a number of cell receptors and channels. NHERF contains two amino-terminal
PDZ (postsynaptic density 95/disk-large/zonula occluden-1) domains that bind to the
cytoplasmic domains of a number of membrane channels or receptors. The carboxyl
terminus of NHERF interacts with the FERM domain (a domain shared by protein 4.1, ezrin,
radixin, and moesin) of a family of actin-binding proteins, ezrin-radixin-moesin. NHERF was …
organizing a number of cell receptors and channels. NHERF contains two amino-terminal
PDZ (postsynaptic density 95/disk-large/zonula occluden-1) domains that bind to the
cytoplasmic domains of a number of membrane channels or receptors. The carboxyl
terminus of NHERF interacts with the FERM domain (a domain shared by protein 4.1, ezrin,
radixin, and moesin) of a family of actin-binding proteins, ezrin-radixin-moesin. NHERF was …
