Glomerular structural changes are conventionally investigated by optical or electron
microscopy on two-dimensional (2D) sections. To understand the relationship between
functional and structural changes of glomerular capillary networks in more detail, three-
dimensional (3D) investigation of the capillary tufts is required. Since confocal microscopy
and scanning electron microscopy cannot completely show the 3D topological organization
of the capillary tuft, we have developed an automatic method to obtain a 3D model of the …