What determines glomerular capillary permeability?
WM Deen - The Journal of clinical investigation, 2004 - Am Soc Clin Investig
WM Deen
The Journal of clinical investigation, 2004•Am Soc Clin InvestigThere have been exciting recent advances in our understanding of the structural and
molecular biology of the glomerular slit diaphragm, as described in a report in this issue of
the JCI. These findings, combined with data on the permeability of the basement membrane
and evidence that the endothelium may be a more important barrier than often supposed,
are allowing a clearer understanding to emerge of how the 3 parts of the glomerular
capillary wall jointly determine its functional properties.
molecular biology of the glomerular slit diaphragm, as described in a report in this issue of
the JCI. These findings, combined with data on the permeability of the basement membrane
and evidence that the endothelium may be a more important barrier than often supposed,
are allowing a clearer understanding to emerge of how the 3 parts of the glomerular
capillary wall jointly determine its functional properties.
There have been exciting recent advances in our understanding of the structural and molecular biology of the glomerular slit diaphragm, as described in a report in this issue of the JCI. These findings, combined with data on the permeability of the basement membrane and evidence that the endothelium may be a more important barrier than often supposed, are allowing a clearer understanding to emerge of how the 3 parts of the glomerular capillary wall jointly determine its functional properties.
The Journal of Clinical Investigation