Immunologic principles and immunotherapeutic approaches in ovarian cancer
KL Knutson, TJ Curiel, L Salazar… - Hematology/Oncology …, 2003 - hemonc.theclinics.com
Immune-based therapies for the treatment of ovarian cancer now are being designed to
circumvent specific biologic problems that have been identified from studies of the native
immune response to ovarian cancer. Advances in basic immunology in the 1990s have
resulted in the development of immune-based therapies for ovarian cancer. Perhaps the
most important advances are the understanding that ovarian tumors are immunogenic and
the identification of tumor-specific antigens. Some of the identified tumor antigens are …
circumvent specific biologic problems that have been identified from studies of the native
immune response to ovarian cancer. Advances in basic immunology in the 1990s have
resulted in the development of immune-based therapies for ovarian cancer. Perhaps the
most important advances are the understanding that ovarian tumors are immunogenic and
the identification of tumor-specific antigens. Some of the identified tumor antigens are …