The nuclear envelope and human disease

A Muchir, HJ Worman - Physiology, 2004 - journals.physiology.org
A Muchir, HJ Worman
Physiology, 2004journals.physiology.org
Mutations in nuclear lamins A and C, intermediate filament proteins of the nuclear envelope,
cause diseases affecting various tissues and the aging process. We review what is known
about nuclear lamin function and the different diseases caused by mutations in lamins A and
C and associated inner nuclear membrane proteins.
Mutations in nuclear lamins A and C, intermediate filament proteins of the nuclear envelope, cause diseases affecting various tissues and the aging process. We review what is known about nuclear lamin function and the different diseases caused by mutations in lamins A and C and associated inner nuclear membrane proteins.
American Physiological Society