[CITATION][C] Insights into the chemistry and biology of the I-Ag7 class II molecule
E Carrasco-Marin, O Kanagawa, ER Unanue - Research in immunology, 1997 - Elsevier
During antigen presentation, the protein antigen must be processed intracellularly by
antigen-presenting cells (APC)(Ziegler and Unanue, 1981, 1982) in order to generate
peptides that, bound to major histocompatibility complex (MHC) class II molecules, are then
presented to CD4 T cells (Babbitt et al., 1985; Allen et al., 1985). A number of studies have
analysed the molecular and structural basis of the interaction between class II molecules
and diverse peptides (for examples, Hunt et al., 1992; Chicz et al. 1992; Nelson et al., 1992; …
antigen-presenting cells (APC)(Ziegler and Unanue, 1981, 1982) in order to generate
peptides that, bound to major histocompatibility complex (MHC) class II molecules, are then
presented to CD4 T cells (Babbitt et al., 1985; Allen et al., 1985). A number of studies have
analysed the molecular and structural basis of the interaction between class II molecules
and diverse peptides (for examples, Hunt et al., 1992; Chicz et al. 1992; Nelson et al., 1992; …