Neutrophil activation in acute renal failure and sepsis

WH Hörl, RM Schäfer, M Hörl, A Heidland - Archives of Surgery, 1990 - jamanetwork.com
• Neutrophils are activated during sepsis. To find out whether granulocytes are further
activated during hemodialysis with cellulosic and noncellulosic membranes, we compared
the plasma levels of the main granulocyte components in patients with chronic uremia who
were undergoing regular hemodialysis treatment and patients with acute renal failure with
and without sepsis. During hemodialysis with cuprophane dialyzers, plasmagranulocyte
elastase, in complex with α-proteinase inhibitor, and lactoferrin levels increased in patients …