[HTML][HTML] Two Arabidopsis metacaspases AtMCP1b and AtMCP2b are arginine/lysine-specific cysteine proteases and activate apoptosis-like cell death in yeast
N Watanabe, E Lam - Journal of Biological Chemistry, 2005 - ASBMB
Metacaspases in plants, fungi, and protozoa constitute new members of a conserved
superfamily of caspase-related proteases. A yeast caspase-1 protein (Yca1p), which is the
single metacaspase in Saccharomyces cerevisiae, was shown to mediate apoptosis
triggered by oxidative stress or aging in yeast. To examine whether plant metacaspase
genes are functionally related to YCA1, we carried out analyses of AtMCP1b and AtMCP2b,
representing the two subtypes of the Arabidopsis metacaspase family, utilizing yeast strains …
superfamily of caspase-related proteases. A yeast caspase-1 protein (Yca1p), which is the
single metacaspase in Saccharomyces cerevisiae, was shown to mediate apoptosis
triggered by oxidative stress or aging in yeast. To examine whether plant metacaspase
genes are functionally related to YCA1, we carried out analyses of AtMCP1b and AtMCP2b,
representing the two subtypes of the Arabidopsis metacaspase family, utilizing yeast strains …