Dietary polyunsaturated fats uniquely suppress rat liver fatty acid synthase and S14 mRNA content
SD Clarke, MK Armstrong, DB Jump - The Journal of nutrition, 1990 - Elsevier
The objective of these studies was to demonstrate that dietary polyunsaturated, but not
saturated, fatty acids decrease mRNA abundance for fatty acid synthase (FAS) and S14. A
series of experiments involving adult and weanling rats was designed to examine the ability
of saturated (tripalmitin),(n-9) monounsaturated (triolein),(n-6) di-unsaturated (safflower oil),
and (n-3) polyenic (fish oil) fatty acids to suppress the gene expression of FAS and S14.
Dietary polyunsaturated fats reduced by 75–90% the hepatic abundance of FAS and S14 …
saturated, fatty acids decrease mRNA abundance for fatty acid synthase (FAS) and S14. A
series of experiments involving adult and weanling rats was designed to examine the ability
of saturated (tripalmitin),(n-9) monounsaturated (triolein),(n-6) di-unsaturated (safflower oil),
and (n-3) polyenic (fish oil) fatty acids to suppress the gene expression of FAS and S14.
Dietary polyunsaturated fats reduced by 75–90% the hepatic abundance of FAS and S14 …