Antagonism of NPY-induced feeding by pretreatment with cyclic AMP response element binding protein antisense oligonucleotide
WT Chance, S Sheriff, F Peng, A Balasubramaniam - Neuropeptides, 2000 - Elsevier
Although second messenger systems subserving neuropeptide Y (NPY)-mediated
behaviors have been identified for a variety of receptors in several tissues, downstream
signaling events are not well known. The nuclear binding protein, cyclic AMP response
element binding protein (CREB) appears to be a transcription factor that is activated
following injection of NPY into rat hypothalamus. To allow determination of the functional
nature of CREB mediation of NPY-induced feeding, injection cannulae were implanted into …
behaviors have been identified for a variety of receptors in several tissues, downstream
signaling events are not well known. The nuclear binding protein, cyclic AMP response
element binding protein (CREB) appears to be a transcription factor that is activated
following injection of NPY into rat hypothalamus. To allow determination of the functional
nature of CREB mediation of NPY-induced feeding, injection cannulae were implanted into …