[HTML][HTML] The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation

F Martinon, K Hofmann, J Tschopp - Current Biology, 2001 - cell.com
F Martinon, K Hofmann, J Tschopp
Current Biology, 2001cell.com
In pro-apoptotic signaling pathways, the interaction between the different initiator units such
as the death receptor Fas, the various adaptor proteins and caspases is primarily mediated
by three structurally related protein–protein domains called death domain (DD), death
effector domain (DED), and caspase-recruitment domain (CARD)[
In pro-apoptotic signaling pathways, the interaction between the different initiator units such as the death receptor Fas, the various adaptor proteins and caspases is primarily mediated by three structurally related protein–protein domains called death domain (DD), death effector domain (DED), and caspase-recruitment domain (CARD)[
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