Randomized double-blind study of potassium citrate in idiopathic hypocitraturic calcium nephrolithiasis
P Barcelo, O Wuhl, E Servitge, A Rousaud… - The Journal of …, 1993 - Elsevier
In an attempt to document the efficacy of potassium citrate in stone formation, 57 patients
with active lithiasis (2 or more stones during the preceding 2 years) and hypocitraturia were
randomly allocated into 2 groups, with 1 group taking 30 to 60 mEq. potassium citrate daily
in wax matrix tablet formation and the other group receiving placebo. In 18 patients receiving
potassium citrate for 3 years stone formation significantly declined after treatment from
1.2±0.6 to 0.1±0.2 per patient year (p< 0.0001), in 13 patients (72%) the disease was in …
with active lithiasis (2 or more stones during the preceding 2 years) and hypocitraturia were
randomly allocated into 2 groups, with 1 group taking 30 to 60 mEq. potassium citrate daily
in wax matrix tablet formation and the other group receiving placebo. In 18 patients receiving
potassium citrate for 3 years stone formation significantly declined after treatment from
1.2±0.6 to 0.1±0.2 per patient year (p< 0.0001), in 13 patients (72%) the disease was in …