Major risk factors as antecedents of fatal and nonfatal coronary heart disease events
P Greenland, MD Knoll, J Stamler, JD Neaton, AR Dyer… - Jama, 2003 - jamanetwork.com
ContextA frequently cited concept is that individual major risk factors for coronary heart
disease (CHD) are absent in many patients (perhaps> 50%) with CHD. However, prior
studies have not systematically evaluated the extent to which CHD patients have previous
exposure to at least 1 risk factor, including diabetes, cigarette smoking, or clinically elevated
levels of cholesterol or blood pressure. ObjectiveTo determine the frequency of exposure to
major CHD risk factors. Design, Setting, and ParticipantsThree prospective cohort studies …
disease (CHD) are absent in many patients (perhaps> 50%) with CHD. However, prior
studies have not systematically evaluated the extent to which CHD patients have previous
exposure to at least 1 risk factor, including diabetes, cigarette smoking, or clinically elevated
levels of cholesterol or blood pressure. ObjectiveTo determine the frequency of exposure to
major CHD risk factors. Design, Setting, and ParticipantsThree prospective cohort studies …
