Effects of S-adenosylmethionine on lipid peroxidation and liver fibrogenesis in carbon tetrachloride-induced cirrhosis

M Gassó, M Rubio, G Varela, M Cabré, J Caballería… - Journal of …, 1996 - Elsevier
Background/Aim: The aim of this study was to investigate the effects of S-
adenosylmethionine on liver peroxidation and liver fibrogenesis in carbon tetrachloride-
induced cirrhosis. Methods: Cirrhosis was induced in three groups of six rats by repeated
injections of carbon tetrachloride over 9 weeks. One group of animals was treated with
carbon tetrachloride, and the other two received carbon tetrachloride plus S-adenosyl-
methionine (10 mg/kg intramuscularly daily) from week 3 to week 9, and from week 6 to …