Unraveling the mission of FcϵRI on antigen-presenting cells
N Novak, S Kraft, T Bieber - Journal of allergy and clinical immunology, 2003 - Elsevier
A decade ago, the discovery of the high-affinity receptor for IgE (FcϵRI) on epidermal
Langerhans cells documented the end of the dogma that FcϵRI is only expressed on
effector cells of anaphylaxis. Since then, the functional significance of this receptor on
antigen-presenting cells (APCs) has been an area of intense research work. Scientists have
focused on a better understanding of the molecular structure, regulation, and role of FcϵRI
on APCs in the human immune system. Insights into the cellular events linked to the …
Langerhans cells documented the end of the dogma that FcϵRI is only expressed on
effector cells of anaphylaxis. Since then, the functional significance of this receptor on
antigen-presenting cells (APCs) has been an area of intense research work. Scientists have
focused on a better understanding of the molecular structure, regulation, and role of FcϵRI
on APCs in the human immune system. Insights into the cellular events linked to the …