Role of fucosyltransferases in leukocyte trafficking: major impact for cutaneous immunity
AJ Schottelius, A Hamann, K Asadullah - Trends in immunology, 2003 - cell.com
AJ Schottelius, A Hamann, K Asadullah
Trends in immunology, 2003•cell.comRecent papers on the role of fucosyltransferase VII (FucTVII) in leukocyte trafficking
underscore the importance of this glycosyltransferase for selectin ligand synthesis,
inflammation and skin homing. Furthermore, other data have shown how another
transferase, FucTIV, might compensate for FucTVII functions and contribute to the generation
of functional binding epitopes involved in tethering and rolling functions.
underscore the importance of this glycosyltransferase for selectin ligand synthesis,
inflammation and skin homing. Furthermore, other data have shown how another
transferase, FucTIV, might compensate for FucTVII functions and contribute to the generation
of functional binding epitopes involved in tethering and rolling functions.
Abstract
Recent papers on the role of fucosyltransferase VII (FucTVII) in leukocyte trafficking underscore the importance of this glycosyltransferase for selectin ligand synthesis, inflammation and skin homing. Furthermore, other data have shown how another transferase, FucTIV, might compensate for FucTVII functions and contribute to the generation of functional binding epitopes involved in tethering and rolling functions.
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