Analysing uncharted transcriptomes with SAGE

VE Velculescu, B Vogelstein, KW Kinzler - Trends in Genetics, 2000 - cell.com
Trends in Genetics, 2000cell.com
Methods of comprehensive gene expression analysis have traditionally been limited to
analysing bulk tissue or millions of cells. New modifications of serial analysis of gene
expression (SAGE) have now permitted the analysis of gene expression in cell
subpopulations or microanatomic structures, providing access to unexplored transcriptomes
of normal and disease biology.
Abstract
Methods of comprehensive gene expression analysis have traditionally been limited to analysing bulk tissue or millions of cells. New modifications of serial analysis of gene expression (SAGE) have now permitted the analysis of gene expression in cell subpopulations or microanatomic structures, providing access to unexplored transcriptomes of normal and disease biology.
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