Modulation of high-affinity IgE receptor expression in blood monocytes: opposite effect of IL-4 and glucocorticoids
P Gosset, C Lamblin-Degros, I Tillie-Leblond… - Journal of allergy and …, 2001 - Elsevier
Background: The expression of high-affinity IgE receptor (FcϵRI) is increased in blood
monocytes (BMs) from allergic patients compared with those of nonatopic subjects (NASs).
Objective: We investigated the in vitro effect of cytokines involved in allergic diseases on the
modulation of FcϵRI expression in BMs from allergic asthmatic patients (AAPs) and NASs.
The influence of in vitro and in vivo treatments with glucocorticoids (GCs) was also
assessed. Methods: FcϵRI α-chain expression on BMs evaluated by flow cytometry analysis …
monocytes (BMs) from allergic patients compared with those of nonatopic subjects (NASs).
Objective: We investigated the in vitro effect of cytokines involved in allergic diseases on the
modulation of FcϵRI expression in BMs from allergic asthmatic patients (AAPs) and NASs.
The influence of in vitro and in vivo treatments with glucocorticoids (GCs) was also
assessed. Methods: FcϵRI α-chain expression on BMs evaluated by flow cytometry analysis …