(Beta2-glycoprotein) I-dependent anticardiolipin antibodies as risk factor for reactions in borderline leprosy patients

P Fiallo, E Nunzi, PP Cardo - International Journal of Leprosy …, 1998 - search.proquest.com
P Fiallo, E Nunzi, PP Cardo
International Journal of Leprosy and Other Mycobacterial Diseases, 1998search.proquest.com
Leprosy reactions are inflammatory acute episodes that alter the uneventful clinical course
of leprosy. Leprosy reactions may be severe and cause irreversible damage to the eye and
nerves. Although they represent acute hypersensitivity reactions, their pathogenesis and the
predisposing factors are yet to be fully elucidated.Immune responses to a wide range of
antigens, not necessarily specific to Mycobacterium leprae (3), are often seen in leprosy
patients. Anticardiolipin (aCL) antibodies have been reported (1, 4), but their relationship to …
Leprosy reactions are inflammatory acute episodes that alter the uneventful clinical course of leprosy. Leprosy reactions may be severe and cause irreversible damage to the eye and nerves. Although they represent acute hypersensitivity reactions, their pathogenesis and the predisposing factors are yet to be fully elucidated.
Immune responses to a wide range of antigens, not necessarily specific to Mycobacterium leprae (3), are often seen in leprosy patients. Anticardiolipin (aCL) antibodies have been reported (1, 4), but their relationship to the pathogenesis, clinical course or prognosis of leprosy is not known.
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