Antihuman immunoglobulin affinity immunoadsorption strongly decreases proteinuria in patients with relapsing nephrotic syndrome.

J Dantal, Y Godfrin, R Koll, S Perretto… - Journal of the …, 1998 - journals.lww.com
Approximately 20 to 30% of patients with idiopathic nephrotic syndrome and focal
glomerulosclerosis experience a relapse of their nephrotic syndrome after transplantation.
Previously, it has been shown that ex vivo immunoadsorption on protein A strongly
(although transiently) reduces proteinuria in relapsing patients. To investigate whether the
factor (s) that give rise to albuminuria are bound directly to protein A in the
immunoadsorption procedure or are part of a complex with Ig, four patients with relapse of …