Renal transplantation is a treatment, not a cure. Although transplantation may return renal
function to the recipient, it does not necessarily remove the cause of the recipient's original
renal disease. Glomerulonephritis is the cause of renal failure for 20 to 40% of those who
receive a transplant; for these recipients, the threat of recurrent disease is real. The
transplant setting of immunosuppression, different antigenic characteristics of the graft
versus the native kidney, and different chronology may attenuate or prevent recurrence of …