New insights into the understanding of asthma
RJ Davies, J Wang, MM Abdelaziz, MA Calderon… - Chest, 1997 - Elsevier
The prevalence of asthma is increasing, despite better understanding of its pathogenesis
and improved treatments. During the past 10 years, the perception of asthma has shifted
from a disease primarily characterized by altered smooth muscle function to one mainly
characterized by chronic inflammation. This article reviews the evidence supporting the
relationship of inflammation in both the upper and lower airways, focusing on intermittent
seasonal disease as well as on the more chronic and severe forms of asthma, including that …
and improved treatments. During the past 10 years, the perception of asthma has shifted
from a disease primarily characterized by altered smooth muscle function to one mainly
characterized by chronic inflammation. This article reviews the evidence supporting the
relationship of inflammation in both the upper and lower airways, focusing on intermittent
seasonal disease as well as on the more chronic and severe forms of asthma, including that …
